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Fujirebio INNO-LiPA® CFTR 17+Tn Update

Analysis of 36 CFTR mutations and wild types, plus CBAVD-related Tn polymorphism

INNO-LiPA CFTR is a multiparameter line probe assay, based on the reverse hybridization principle, for the simultaneous detection and identification of 36 Cystic Fibrosis-related mutations and their wild-type sequences in human whole blood, dried blood spots, and buccal brush samples.

In addition, probes for the identification of the Tn polymorphism within intron 8 are included.

For the detection and identification of all 36 mutations, the INNO-LiPA CFTR 19 and INNO-LiPA CFTR 17+Tn Update kits are required.

Features & Benefits

  • Two strips replace multiple testing.
  • The INNO-LiPA CFTR provides probes for the 36 most frequent CFTR-related mutations worldwide.
  • The combination of the 2 strips also covers the panel of CFTR mutations recommended by the ACMG/ACOG (23 mutations).
  • Analysis of both the mutant and the wild-type sequences demonstrates homo- or heterozygosity for each tested mutation, allowing the discrimination between carrier status and patients. 
  • The test is fast and easy to perform, offers quick visual interpretation, and full results are obtained within one working day. 
  • Fully automated processing of the strips is possible using Auto-LiPA™ 48 and AutoBlot 3000H.
  • Objective, automated reading and interpretation of the strips is possible using LiRAS® for LiPA Cystic Fibrosis.

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