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Fujirebio INNO-LIA® HTLV I/II Score

Finally, a clear answer in HTLV confirmation 

Line immunoassay for the confirmation and discrimination of antibodies to Human T-cell Lymphotrophic Virus type I (HTLV-I) and type II (HTLV-II) in human serum and plasma.

The assay uses well-defined antigens derived from HTLV I and HTLV II immunodominant proteins.

The antigens are either recombinant proteins or synthetic peptides that are purified and fixed on a nylon membrane.

The antigenicity exhibited by these proteins and peptides is either common to HTLV I and HTLV II antibodies or type-specific to one of the two viruses allowing confirmation and discrimination in a single assay.

Two gag bands (p19 I/II, p24 I/II) and two env (gp46 I/II, gp21 I/II) bands are applied as non-type-specific antigens, used to confirm the presence of antibodies against HTLV I/II.

The type-specific antigens (gag p19-I, env gp46-I) specific for HTLV I and (env gp46-II) specific for HTLV II, enable differentiation of HTLV I and HTLV II infections.

Features & Benefits

  • Complete answer in one test: confirmation and discrimination
  • Low follow-up rate
  • Low indeterminate rate
  • Optimal specificity in screened-negative blood donors: 99.7% (304/305)
  • Optimal sensitivity for HTLV I (100%; 218/218) and HTLV II (100%; 112/112)
  • Colour-coded reagents
  • Ready-to-use reagents
  • Four control lines to monitor 1) non-specific reactivity, 2) sample addition,  3) and 4) colour development steps
  • Fully automated strip processing possible using TENDIGO™, Auto-LIA™ 48 or AutoBlot 3000(H)
  • Objective, automated reading and interpretation of the strips possible using LiRAS® for Infectious Diseases

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