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Fujirebio INNO-LiPA® HLA-B Update Plus

Detects all known alleles of HLA-B with one amplification and two strips.

Bw4/Bw6 ambiguities can be resolved by an additional Bw4-specific amplification and hybridization on one strip.

INNO-LiPA HLA-B Update Plus is a line probe assay for the molecular typing of human leukocyte antigen (HLA) B alleles at allele group level (B*07 – B*83).

Features & Benefits

More informative than serology

  • INNO-LiPA HLA-B Update Plus yields more information on genetic variation
  • New alleles mainly appear as new probe patterns, not blanks
  • Null alleles can be detected


  • Reagents are synthesised and are therefore not limited in quantity
  • Reagents are standardised to show minimal batch-to-batch differences
  • INNO-LiPA HLA-B Update Plus utilises DNA samples that are easy to transport
  • Cell viability or surface expression is not important
  • Two to three strips replace multiple testing


  • INNO-LiPA HLA-B Update Plus can be used for emergency typing as well as for large batch analysis
  • One technician – one to one hundred samples – one working day


  • The LiPA technique is easy to perform
  • Automation is possible using TENDIGO® and Auto-LiPA™ 48
  • Objective interpretation of data with LiRAS® for LiPA HLA software

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